Osteoporosis, bone & mineral

The significance of recent fracture location for imminent risk of hip and vertebral fractures—a nationwide cohort study on older adults in Sweden

Osteoporos IntPublished Retrospective cohort study

Authors' conclusion

Patients with recent fractures had an increased risk of subsequent hip and vertebral fractures, regardless of the index fracture site.

Study context

Population
All Swedes aged 50 years and older between 2007 and 2010, followed until December 2017
Participants
3,423,320 participants
Exposure
Recent (≤ 2 years) index fracture, by site, and old (> 2 years) prevalent fracture vs no prevalent fracture
  • Recent fracturen = 145,780
  • Old fracturen = 293,051
  • No previous fracturen = 2,984,489reference
Outcome
Risk of hip and vertebral fractures during follow-up
Methodological detailsnationwide, Swedish national registers, censoring for death and migration
  • Nationwide
  • Swedish national registers
  • Censoring for death and migration

Main finding

As reported in the abstract

  • Recent fracture at almost all sites: significantly increased risk of hip fracture vs controls
  • Recent fracture at almost all sites: elevated risk of vertebral fracture vs controls
  • Recent fractures: increased risk of subsequent hip and vertebral fractures, regardless of index fracture site

Observational data: associations, not effects.

Further findings

Follow-up time

Original publication

The significance of recent fracture location for imminent risk of hip and vertebral fractures—a nationwide cohort study on older adults in Sweden. Osteoporos Int. Published 23 March 2024. doi:10.1007/s00198-024-07072-x

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