The Importance of Recent Prevalent Fracture Site for Imminent Risk of Fracture – A Retrospective, Nationwide Cohort Study of Older Swedish Men and Women
Authors' conclusion
All recent fractures, MOFs, and non-MOFs, as well as older fractures, increase the risk of subsequent fracture
Study context
- Population
- All Swedes aged ≥50 years between 2007 and 2010; followed until December 31, 2017
- Participants
- 3,423,320 participants
- Exposure
- Recent major osteoporotic fracture (MOF), recent non-MOF and old fracture vs no previous fracture
- Recent MOFn = 70,254
- Recent non-MOFn = 75,526
- Old fracturen = 293,051
- Controlsn = 2,984,489reference
- Outcome
- Risk of any fracture
Methodological detailsnationwide, national registers
- Nationwide
- National registers
Main finding
As reported in the abstract
Any fracture
Each group vs controlsHazard ratio (95% CI)
Recent MOF
2.11(2.08–2.14)
Recent non-MOF
2.24(2.21–2.27)
Old fracture
1.77(1.76–1.78)
Observational data: associations, not effects.
Further findings
Follow-up time
Original publication
The Importance of Recent Prevalent Fracture Site for Imminent Risk of Fracture – A Retrospective, Nationwide Cohort Study of Older Swedish Men and Women. J Bone Miner Res. Published 27 March 2023. doi:10. 1002/ jbmr. 4806
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