Osteoporosis, bone & mineral

The recurrence of osteoporotic fractures among first- and second-generation immigrants in Sweden

Osteoporos IntPublished Nationwide open cohort study

Authors' conclusion

Among first- and second-generation men, the risk of a second fracture was slightly lower than that of native Swedes, while among first- and second-generation women, the risk was similar to the reference group.

Study context

Population
Individuals ≥ 50 years with a previous osteoporotic fracture (hip, humerus, forearm, vertebrae or pelvis), Swedish National Patient Register, 2010–2018with a previous fracture
Participants
296,118 individuals
Exposure
First- and second-generation immigrants vs Swedish-born individuals with Swedish-born parents
Outcome
Second (recurrent) osteoporotic fracture
Methodological detailslogistic regression, stratified by sex, adjusted for age, comorbidities and sociodemographic status
  • Logistic regression
  • Stratified by sex
  • Adjusted for age, comorbidities and sociodemographic status

Main finding

As reported in the abstract

Second osteoporotic fracture after a first osteoporotic fracture (fully adjusted OR)
Odds ratio (95% CI)
Foreign-born menfully adjusted; referents: Swedish-born men with Swedish-born parents
0.90(0.82–0.98)
Foreign-born womenfully adjusted; referents: Swedish-born women with Swedish-born parents
0.95(0.91–1.00)
Men with foreign-born parentsfully adjusted; referents: Swedish-born men with Swedish-born parents
0.85(0.73–0.99)
Women with foreign-born parentsfully adjusted; referents: Swedish-born women with Swedish-born parents
1.00(0.91–1.09)

Observational data: associations, not effects.

Further findings

Second fracture by region of origin

Significantly lower odds: men from Asia; women from Eastern Europe, Baltic countries, Asia and Latin America; men with parents from the Nordic countries

Fractures registered

First-generation study (men n = 7,428; women n = 25,744)
33,172
Second-generation study (men n = 3,607; women n = 9,372)
12,979

Original publication

The recurrence of osteoporotic fractures among first- and second-generation immigrants in Sweden. Osteoporos Int. Published 17 February 2026. doi:10.1007/s00198-026-07901-1

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