The Role of Hypogonadism in the Body Composition of Obese Men in the Preoperative Period of Bariatric Surgery
Authors' conclusion
Hypogonadism was identified in at least 23% of patients. Considering TT below the lower limit of normality for characterization of hypogonadism, we identified a significant worsening in body composition parameters.
Study context
- Population
- Obese men in the preoperative period of bariatric surgery, 2 obesity referral centers, June 2019–December 2021; mean age 35.6 ± 8.8 years, mean body mass index (BMI) 42.3 ± 4.7 kg/m²
- Participants
- 30 men
- Exposure
- Hypogonadal vs eugonadal obese men
- Outcome
- Prevalence of hypogonadism
Methodological detailspopulation-based, 2 obesity referral centers
- Population-based
- 2 obesity referral centers
Main finding
As reported in the abstract
Hypogonadism with TT <264 ng/dL
22 patients
73%
Hypogonadism with TT <164 ng/dL
7 patients
23%
Observational data: associations, not effects.
Further findings
Mean TT, cut-off TT <164 ng/dL
P < 0.001
Weight, cut-off TT <164 ng/dL
P = 0.036
Fat mass (FM-kg), cut-off TT <164 ng/dL
P = 0.007
BMI, cut-off TT <164 ng/dL
P = 0.014
Body fat percentage (FM-%), cut-off TT <164 ng/dL
P = 0.010
| Outcome | Hypogonadal | Eugonadal | P value |
|---|---|---|---|
| Mean TT, cut-off TT <264 ng/dL | mean 198.9 (68.7) ng/dL | mean 357.0 (59.5) ng/dl | P < 0.001 |
Positive ADAM questionnaire screening
- Positive screening, no significant difference between groups
- 93.3%
Body composition, cut-off TT <264 ng/dL
- No statistically significant difference in body composition between groups
Original publication
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