Effect of a low‐carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial
Primary result · Pain now (Brief Pain Inventory)Result — go to the resultDifference −1.1 95% CI −1.9 to −0.3Authors' conclusion
Diet-induced weight loss in women with lipedema can improve QoL. An energy-restricted LCD seems to be superior to a standard control diet in reducing pain.
Study context
- Population
- Adult female patients with lipedema and obesity; mean age 47 (SD 11) years, BMI 37 (SD 5) kg/m²
- Participants
- 70 patients
- Comparison
- Low-carbohydrate diet vs control diet, both 1200 kcal/day, for 8 weeks
- Primary endpoint
- Pain (Brief Pain Inventory)
- Follow-up
- 8 weeks
Primary result
Pain now (Brief Pain Inventory) · postintervention (8 weeks)
Difference
−1.1
95% CI −1.9 to −0.3
P = 0.009
LCDvs Control
difference −1.1 (95% CI −1.9 to −0.3); P = 0.009
As reported in the abstract
Secondary outcomes
| Outcome | Difference (kg) (95% CI) | P value | |
|---|---|---|---|
| Weight loss · 8 weeksGreater weight loss with LCD | −2.8 (−4.1 to −1.0) | P < 0.001 | |
| −6−4−202Difference, kg (linear scale) |
Association of change in pain now with weight loss
- No association between changes in pain now and weight loss
Quality of life (QoL) (RAND-36, IWQOL-Lite, LYMQOL)
- Both groups improved in several QoL dimensions
Original publication
Effect of a low‐carbohydrate diet on pain and quality of life in female patients with lipedema: a randomized controlled trial. Obesity (Silver Spring). Published 16 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →