Gestational diabetes & diabetes in pregnancy
The need for pharmacotherapy among patients with one or more elevations on glucose tolerance test
Authors' conclusion
Among patients with 1 OGTT elevation, fasting elevation and BMI are predictive of need for anti-glycemic medications. Predictive models may be useful in assessing need for pharmacotherapy for patients with abnormal OGTT, not otherwise meeting criteria for gestational diabetes.
Study context
- Population
- Singleton gestations ≥24 weeks with at least 1 elevation on 3-hour oral glucose tolerance test (OGTT)
- Participants
- 480 vs 376
- Exposure
- Timing, number and extent of OGTT elevations as predictors of need for pharmacotherapy
- 1 OGTT elevationn = 480reference
- ≥2 OGTT elevationsn = 376
- Outcome
- Need for pharmacotherapy for glycemic control
Methodological detailslogistic regression, predictive model based on linear discriminant analysis
- Logistic regression
- Predictive model based on linear discriminant analysis
Main finding
As reported in the abstract
1 OGTT elevation
19.2%
Observational data: associations, not effects.
Further findings
Predictive model (body mass index (BMI) and extent of elevation at each OGTT time point)
- Increase in identification of patients requiring pharmacotherapy
- 15.4%
Original publication
The need for pharmacotherapy among patients with one or more elevations on glucose tolerance test. J Clin Endocrinol Metab. Published 12 February 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →