The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle
Authors' conclusion
While there is a strong genetic component to the development of type 2 diabetes, it is often triggered by lifestyle or environmental factors. Understanding the genetics that lead to the development of type 2 diabetes in sib-pairs when compared to the inherent environmental and lifestyle risk factors may lead to the development of new therapeutic and preventive strategies.
Study context
- Population
- Sib-pairs living with T2D in the South-South region of Nigeria250 sib-pairs planned
- Outcome
- Genetic, environmental and lifestyle factors associated with the development of T2D amongst sib-pairs, and which is more prominent
Methodological detailsstudy protocol, multicentre, comparative exploratory, simple consecutive sampling, Assessment of bio-psycho-social and environmental risk factors by structured survey instrument, Blood samples for multi-omic studies analysed for genetic and environmental factors
- Study protocol
- Multicentre
- Comparative exploratory
- Simple consecutive sampling
- Assessment of bio-psycho-social and environmental risk factors by structured survey instrument
- Blood samples for multi-omic studies analysed for genetic and environmental factors
Main finding
As reported in the abstract
- No results reported (protocol); most common genetic factors to be explored and their contribution compared with lifestyle and environmental factors
Observational data: associations, not effects.
Original publication
The development of type 2 diabetes amongst sibling pairs in the South‐South region of Nigeria: The effect of genetics, environment and lifestyle. Diabet Med. Published 1 April 2026. doi:10.
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