Sweetened beverages and atrial fibrillation in people with prediabetes or diabetes
Authors' conclusion
Both the intake of SSBs and ASBs were linearly and positively associated with new-onset AF, while NJ intake did not show a significant association with AF in people with prediabetes or diabetes. Replacing an equivalent amount of SSB intake with NJs, but not ASBs, was associated with a lower risk of AF.
Study context
- Population
- People with prediabetes or diabetes, UK Biobank; beverage intake by 24-hour dietary recalls 2009–2012
- Participants
- 31,433 people
- Exposure
- Intake of Sugar-sweetened Beverages (SSBs), Artificially Sweetened Beverages (ASBs) and Natural Juices (NJs)
- Outcome
- New-onset AF
- Follow-up
- Median 12.0 years
Methodological detailsUK Biobank, 24-hour dietary recalls
- UK Biobank
- 24-hour dietary recalls
Main finding
As reported in the abstract
New-onset AF, per 1 unit/day increment
Adjusted HR per 1 unit/day (95% CI)
SSBslinear, positive association
1.11(1.04–1.18)
ASBslinear, positive association
1.08(1.02–1.14)
NJs
1.00(0.93–1.08)
Per 1 unit/day increment, as printed
- Atrial fibrillation (AF) cases documented
- 2470 (7.9%)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted HR (95% CI) | |
|---|---|---|
| New-onset AF, >1 unit/day vs non-consumersSSBsvs Non-consumers | 1.30 (1.11–1.53) | |
| New-onset AF, >1 unit/day vs non-consumersASBsvs Non-consumers | 1.21 (1.05–1.40) | |
| New-onset AF, substitution of 1 unit/day for SSBsNJsvs SSBs9% lower risk | 0.91 (0.83–0.99) | |
| New-onset AF, substitution of 1 unit/day for SSBsASBsvs SSBs | 0.97 (0.89–1.06) | |
| 0.512Adjusted hazard ratio (log scale) |
Original publication
Sweetened beverages and atrial fibrillation in people with prediabetes or diabetes. Diabetes Obes Metab. Published 19 August 2024. doi:10.
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