Type 2 & other diabetes

Associations Between Beverage Consumption and Risk of Microvascular Complications Among Individuals With Type 2 Diabetes

J Clin Endocrinol MetabPublished Prospective cohort study

Authors' conclusion

Higher consumption of ASBs and SSBs was linearly associated with an increased risk of microvascular complications in adults with T2D.

Study context

Population
Adults with T2D free of macrovascular and microvascular complications at baseline, UK Biobank1,116 cases
Participants
6,676 adults
Exposure
Beverage consumption vs nonconsumers
Outcome
Composite microvascular complications
Follow-up
Median 11.7 years
Methodological detailsUK Biobank, multivariable-adjusted Cox proportional hazard models
  • UK Biobank
  • Multivariable-adjusted Cox proportional hazard models

Main finding

As reported in the abstract

Multivariable adjusted
Each group vs nonconsumersHazard ratio (95% CI)
ASBs ≥2.0 units/day
1.44(1.18–1.75)
SSBs ≥2.0 units/day
1.32(1.00–1.76)

Observational data: associations, not effects.

Further findings

OutcomeHR (95% CI)
DRTea ≥4.0 units/dayvs NonconsumersHigher tea consumption associated with lower risk0.72 (0.57–0.92)

Diabetic neuropathy

No significant association between individual beverage consumption and risk of diabetic neuropathy

Coffee, natural juice, yogurt

No significant association with risks of microvascular complications

Substitution of half unit/day of artificially sweetened beverages (ASBs) or sugar-sweetened beverages (SSBs) with tea or coffee

Lower risk of microvascular complications
16% to 28%

Original publication

Associations Between Beverage Consumption and Risk of Microvascular Complications Among Individuals With Type 2 Diabetes. J Clin Endocrinol Metab. Published 12 April 2024. doi:10.1210/clinem/dgae242

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