Subclinical Hypothyroidism as an Independent Predictor of Cardiovascular Prognosis in Left Ventricular Thrombus Patients
Main finding · MACCEsResult — go to the resultHazard ratio 1.774 95% CI 1.053–2.989Authors' conclusion
Subclinical hypothyroidism can be used as an independent predictor of MACCEs in patients with LVT, and there is a clinical value in using subclinical hypothyroidism as an important factor suggesting a poor prognosis in patients with LVT.
Study context
- Population
- Patients diagnosed with left ventricular thrombus (LVT) at Fuwai Hospital over the past 10 years
- Exposure
- Subclinical hypothyroidism or subclinical hyperthyroidism vs normal thyroid function
- Outcome
- Major adverse cardiovascular and cerebrovascular events (MACCEs)
Methodological detailssingle-centre, multivariate Cox proportional hazards models
- Single-centre
- Multivariate Cox proportional hazards models
Main finding
MACCEs
Hazard ratio
1.774
95% CI 1.053–2.989
P = 0.031
SCH
HR 1.774 (95% CI 1.053–2.989); P = 0.031
As reported in the abstract
Observational data: associations, not effects.
Further findings
Cardiovascular death
| HR (95% CI) | P value | ||
|---|---|---|---|
| SCH | 1.986 (1.110–3.553) | P = 0.021 | |
| 0.20.5125Hazard ratio (log scale) |
Prediction of major adverse cardiovascular and cerebrovascular events (MACCEs) including thyroid function
- AUC for 1 year
- 0.715
- AUC for 2 years
- 0.745
- AUC for 3 years
- 0.684
Original publication
Subclinical Hypothyroidism as an Independent Predictor of Cardiovascular Prognosis in Left Ventricular Thrombus Patients. J Clin Endocrinol Metab. Published 11 November 2024. doi:10.
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