Short-Term Diabetic Retinopathy Status in People with Type 1 Diabetes Commencing Automated Insulin Delivery
Authors' conclusion
In this study, stable or improved DR grades were evident in most who had recently commenced AID. Age at AID initiation <18 years appears protective.
Study context
- Population
- People aged ≥13 years with T1D after initiation of automated insulin delivery (AID); hospital databases (Dunedin and Christchurch, New Zealand) and two research studies (Auckland, New Zealand; Perth, Australia)
- Participants
- 165 people
- Outcome
- Short-term DR outcomes (change in R- and/or M-grade) after AID initiation
Methodological detailsfour-center
- Four-center
Main finding
As reported in the abstract
DR grade change (R- and/or M-grade) after AID initiation
Improved DR grading
32 of 165
19%
Stable DR grading
99 of 165
60%
Worsened R- and/or M-grade
34 of 165
21%
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| HbA1c improvement | AID mean 1.0 ± 1.3 percentage points |
Risk factors for any worsening of DR
- Age at AID initiation ≥18 years was the only significant risk factor
- P = 0.028
Safety
| Outcome | Values |
|---|---|
| Proliferative change and need for photocoagulation | AID 3% |
- Proliferative change and need for photocoagulation: all had prior DR, diabetes duration >10 years, and at least another diabetes complication or prior DR treatment
Original publication
Short-Term Diabetic Retinopathy Status in People with Type 1 Diabetes Commencing Automated Insulin Delivery. Diabetes Technol Ther. Published 10 February 2025. doi:10.
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