Type 1 diabetes

Sex Differences in Glycemia and Self-management Strategies for Exercise in an Active Adult Cohort With Type 1 Diabetes

J Clin Endocrinol MetabPublished Prospective observational study

Authors' conclusion

Female participants had higher preexercise glucose levels compared to male participants and smaller glucose declines during personal exercise, but there were no observable differences in food, exercise, and insulin habits.

Study context

Population
Adults with T1D, Type 1 Diabetes Exercise Initiative studymatched cohort
Participants
91 vs 91
Exposure
Females vs males
  • Femalesn = 91
  • Malesn = 91reference
Outcome
Glucose levels during and after exercise
Methodological details4-week free-living, matched on age and insulin modality
  • 4-week free-living
  • Matched on age and insulin modality

Main finding

As reported in the abstract

Glucose at start of study exercise

P = 0.01

Observational data: associations, not effects.

Further findings

Glucose at start of personal exercise · higher in females

P = 0.05

Adjusted mean, mmol/L

OutcomeFemaleMaleP value
Glucose decline during study exerciseComparable−0.8−1.0P = 0.11
Glucose decline during personal exercise · smaller decline in females
P < 0.001
24-h mean glucose on sedentary days · higher in females
P = 0.04

Glucose decline during personal exercise

Glucose decline smaller in female participants during personal exercise (adjusted mean)

Macronutrient intake and food, exercise and insulin habits around exercise

Daily macronutrient consumption similar between sexes after adjusting for weight, as were food, exercise and insulin habits surrounding exercise

Original publication

Sex Differences in Glycemia and Self-management Strategies for Exercise in an Active Adult Cohort With Type 1 Diabetes. J Clin Endocrinol Metab. Published 14 November 2024. doi:10.1210/clinem/dgae792

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