Sex Differences in Glycemia and Self-management Strategies for Exercise in an Active Adult Cohort With Type 1 Diabetes
Authors' conclusion
Female participants had higher preexercise glucose levels compared to male participants and smaller glucose declines during personal exercise, but there were no observable differences in food, exercise, and insulin habits.
Study context
- Population
- Adults with T1D, Type 1 Diabetes Exercise Initiative studymatched cohort
- Participants
- 91 vs 91
- Exposure
- Females vs males
- Femalesn = 91
- Malesn = 91reference
- Outcome
- Glucose levels during and after exercise
Methodological details4-week free-living, matched on age and insulin modality
- 4-week free-living
- Matched on age and insulin modality
Main finding
As reported in the abstract
Glucose at start of study exercise
P = 0.01
Observational data: associations, not effects.
Further findings
Glucose at start of personal exercise · higher in females
P = 0.05
Adjusted mean, mmol/L
| Outcome | Female | Male | P value |
|---|---|---|---|
| Glucose decline during study exerciseComparable | −0.8 | −1.0 | P = 0.11 |
- Glucose decline during personal exercise · smaller decline in females
- P < 0.001
- 24-h mean glucose on sedentary days · higher in females
- P = 0.04
Glucose decline during personal exercise
- Glucose decline smaller in female participants during personal exercise (adjusted mean)
Macronutrient intake and food, exercise and insulin habits around exercise
- Daily macronutrient consumption similar between sexes after adjusting for weight, as were food, exercise and insulin habits surrounding exercise
Original publication
Sex Differences in Glycemia and Self-management Strategies for Exercise in an Active Adult Cohort With Type 1 Diabetes. J Clin Endocrinol Metab. Published 14 November 2024. doi:10. 1210/ clinem/ dgae792
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