Exploring Factors That Influence Postexercise Glycemia in Youth With Type 1 Diabetes in the Real World: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study
Authors' conclusion
In this large real-world pediatric exercise study, nocturnal hypoglycemia was higher on nights when average activity duration was higher. Characterizing both participant- and event-level factors that impact glucose in the postexercise recovery period may support development of new guidelines, decision support tools, and refine insulin delivery algorithms to better support exercise in youth with diabetes.
Study context
- Population
- Adolescents with T1D in the T1DEXIP study; mean age 14 ± 2 years, 42% females, hemoglobin A1c (HbA1c) 7.1 ± 1.3%3,319 activities
- Participants
- 251 adolescents
- Outcome
- 24-h postexercise glycemia and hypoglycemia risk
- Follow-up
- 24-h postexercise
Methodological detailsreal-world
- Real-world
Main finding
As reported in the abstract
- Larger glucose drops during exercise associated with lower postexercise mean glucose immediately after activity
- P < 0.001
- Larger glucose drops during exercise associated with lower postexercise mean glucose 12 to <16 h later
- P = 0.02
- Hypoglycemia on nights following exercise vs after sedentary days
- 14% vs 12%
- Nights after exercise: hypoglycemia with average total activity ≥60 min/day vs not
- 17% vs. 8% of nights, P = 0.01
Observational data: associations, not effects.
Original publication
Exploring Factors That Influence Postexercise Glycemia in Youth With Type 1 Diabetes in the Real World: The Type 1 Diabetes Exercise Initiative Pediatric (T1DEXIP) Study. Diabetes Care. Published 27 February 2024. doi:10.
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