Diabetes technology

Performance of three simultaneously used real-time continuous glucose monitoring (rtCGM) systems around a physically active weekend camp in adults with type 1 diabetes: A prospective lab and real‐world study

Diabetes Obes MetabPublished Prospective accuracy study

Authors' conclusion

Dexcom G7 and FreeStyle Libre 3 showed very high accuracy, which could not be found for the Simplera rtCGM system.

Study context

Population
Adults with T1D (9 females; age 50 ± 12 years; HbA1c 6.6 ± 0.5%); 3-day lab phase with three 90-min group exercise sessions, then 4-day home phase
Participants
20 adults
Comparison
Dexcom G7 vs FreeStyle Libre 3 vs Simplera rtCGM accuracy against capillary blood glucose
Outcome
MedARD [IQR] of sensor glucose vs reference capillary blood glucose
Methodological detailslab and real-world phases, simultaneous wear of three rtCGM systems, Duplicate capillary glucose (Contour Next One) every 2 h, 8:00 AM–10:00 PM
  • Lab and real-world phases
  • Simultaneous wear of three rtCGM systems
  • Duplicate capillary glucose (Contour Next One) every 2 h, 8:00 AM–10:00 PM

Performance

As reported in the abstract

MedARD vs reference blood glucose
Test or modelValueComparison points
Dexcom G7median 8.4% (IQR 3.6–14.0)723
Libre 3median 7.5% (IQR 3.1–13.4)723
Simpleramedian 13.8% (IQR 6.9–22.5)719

Value

Dexcom G7median 8.4% (IQR 3.6–14.0)
Libre 3median 7.5% (IQR 3.1–13.4)
Simpleramedian 13.8% (IQR 6.9–22.5)

Comparison points

Dexcom G7723
Libre 3723
Simplera719
  • Libre 3 vs Dexcom G7: P = 0.35 — no significant difference
  • Dexcom G7 vs Simplera: P < 0.0001 — significant difference
  • Libre 3 vs Simplera: P < 0.0001 — significant difference

Original publication

Performance of three simultaneously used rtCGM systems around a physically active weekend camp in adults with type 1 diabetes: A prospective lab and real‐world study. Diabetes Obes Metab. Published 19 December 2025. doi:10.1111/dom.70369

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