Performance of continuous glucose monitoring systems ( continuous glucose monitoring (CGMs) ) during commercial flights in T1DM: A within‐subject comparative pilot study
Authors' conclusion
G7 and Libre3 showed consistently higher accuracy and clinical reliability across various phases of flight and ground conditions. Simplera and i3 exhibited greater variability in accuracy. These findings suggest that while modern CGMs could support diabetes management in aviation, individual system performance may differ under specific operational conditions.
Study context
- Population
- Adults with T1D on commercial flights; age 37.9 ± 12.8 years, HbA1c 52.3 ± 4.9 mmol/mol, diabetes duration 19.25 ± 10.6 years
- Participants
- 20 adults3,473 matched pairs
- Comparison
- Four CGMs during in-flight and ground conditions
- Outcome
- Overall mean absolute relative difference (MARD)
Methodological detailsfour sensors worn in parallel
- Four sensors worn in parallel
Main finding
As reported in the abstract
Overall MARD G7 9.5% ± 3.3% · Libre3 9.6% ± 3.8% · Simplera 19.9% ± 6.2% · i3 15.7% ± 6.6%
%20/20
%10/10
Consensus error grid Zones A and B
Further findings
- Prandial state and flight phase had limited influence on the relative performance ranking of the devices
Original publication
Performance of continuous glucose monitoring systems ( CGMs ) during commercial flights in T1DM: A within‐subject comparative pilot study. Diabetes Obes Metab. Published 2 January 2026. doi:10.
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