A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems
Authors' conclusion
The CGM systems indicated discordant glycemic metrics, which should be considered in diabetes therapy. Different CGM systems should provide the same glucose readings and CGM-derived metrics when used by the same person.
Study context
- Population
- Participants wearing three current-generation CGM systems in parallel for 14 days
- Participants
- 23 participants
- Comparison
- FreeStyle Libre 3 vs Dexcom G7 vs Medtronic Simplera
- Outcome
- CGM-derived glycemic metrics
- Follow-up
- 14 days
Methodological detailsparallel wear of three CGM systems, within-participant comparison
- Parallel wear of three CGM systems
- Within-participant comparison
Main finding
As reported in the abstract
- The apparent glucose profile was influenced by the CGM system, with substantially different glycemic metrics among the three systems
- Agreement between FreeStyle Libre 3 and Dexcom G7 was higher than with Medtronic Simplera, which showed lower glucose levels on average
- Marked intraparticipant discrepancies that would have resulted in different therapeutic recommendations
Original publication
A Comparative Analysis of Glycemic Metrics Derived From Three Continuous Glucose Monitoring Systems. Diabetes Care. Published 8 April 2025. doi:10.
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