Type 2 & other diabetes

Sex differences in cardiometabolic biomarkers during the pre-diabetes stage

Diabetes Res Clin PractPublished Analysis of two prospective epidemiological studies

Authors' conclusion

Sex differences in lipoproteins and vascular inflammatory markers during pre-diabetes indicate sex-specific lipoprotein and inflammatory mechanisms to cardiovascular complications.

Study context

Population
People with pre-diabetes in two large prospective epidemiological studies in the U.S.
Exposure
Women vs men with pre-diabetes
Outcome
Sex differences in cardiometabolic biomarkers

Main finding

As reported in the abstract

  • Women with pre-diabetes had higher adipokine levels
  • Men had lower eGFR
  • Sex differences in lipoproteins and vascular inflammatory markers during pre-diabetes

Observational data: associations, not effects.

Original publication

Sex differences in cardiometabolic biomarkers during the pre-diabetes stage. Diabetes Res Clin Pract. Published 26 July 2023. doi:10.1016/j.diabres.2023.110856

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