Risk Factors for and Risk of Peripheral Artery Disease in Swedish Individuals With Type 2 Diabetes: A Nationwide Register-Based Study
Authors' conclusion
A graded association was observed between increasing number of PAD risk factors not at target and incident PAD in individuals with type 2 diabetes.
Study context
- Population
- Individuals with T2D in the Swedish National Diabetes Register 2005–2009, matched with controls on age, sex and county148,096 with T2D
- Exposure
- T2D by number of peripheral artery disease (PAD) risk factors not at target vs matched controls
- Controlsn = 320,066reference
- Outcome
- Incident PAD
- Follow-up
- 2006 to 2019
Methodological detailsmatched on age, sex and county, Controls who developed T2D during wash-in (<0.2%) were not censored but matched with two new controls
- Matched on age, sex and county
- Controls who developed T2D during wash-in (<0.2%) were not censored but matched with two new controls
Main finding
As reported in the abstract
Each group vs controlsAdjusted hazard ratio (95% CI)
T2D, all risk factors within target
1.41(1.23–1.63)
T2D, all five risk factors not at target
9.28(3.62–23.79)
Observational data: associations, not effects.
Original publication
Risk Factors for and Risk of Peripheral Artery Disease in Swedish Individuals With Type 2 Diabetes: A Nationwide Register-Based Study. Diabetes Care. Published 2 November 2023. doi:10. 2337/ dc23-1198
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