Longitudinal trajectories of glycemic control among U.S. Adults with newly diagnosed diabetes
Authors' conclusion
Claims data identified distinct longitudinal trajectories of HbA1c after diabetes diagnosis, which can be used to anticipate challenges and individualize care plans to improve glycemic control.
Study context
- Population
- US adults with newly diagnosed diabetes, 2005–2018696 (0.58%) T1D
- Participants
- 119,952 adults
- Outcome
- Longitudinal trajectories of HbA1c, overall and by diabetes type
- Follow-up
- 3 years
Methodological detailsclaims data (OptumLabs® Data Warehouse), Mixed Effects Machine Learning trajectory modelling, multinomial regression
- Claims data (OptumLabs® Data Warehouse)
- Mixed Effects Machine Learning trajectory modelling
- Multinomial regression
Main finding
As reported in the abstract
HbA1c trajectories · 3 years
- T1D: diagnosed at very high hemoglobin A1c (HbA1c), partially improved, never achieved control
- 52.6%
- T1D: diagnosed at low HbA1c, deteriorated over time
- 32.5%
- T1D: stable low HbA1c
- 14.9%
- T2D: stable low HbA1c
- 67.7%
- T2D: diagnosed at very high HbA1c, partially improved, never achieved control
- 14.4%
- T2D: diagnosed at moderately high HbA1c, deteriorated over time
- 10.0%
- T2D: diagnosed at moderately high HbA1c, improved over time
- 4.9%
Observational data: associations, not effects.
Original publication
Longitudinal trajectories of glycemic control among U.S. Adults with newly diagnosed diabetes. Diabetes Res Clin Pract. Published 2 November 2023. doi:10.
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