Lipids & metabolic liver disease
Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population
Authors' conclusion
Participants with high levels of baseline TyG index and medium stable or high gradual increase trajectories were associated with an elevated risk of developing CVDs in elderly populations.
Study context
- Population
- Elderly participants, data 2016–2022
- Participants
- 20,185 participants
- Exposure
- Baseline triglyceride-glucose (TyG) index quartiles and TyG trajectories
- Outcome
- Incident CVD
- Follow-up
- Mean 4.25 years
Methodological detailslatent class trajectory model, Cox proportional-hazards models
- Latent class trajectory model
- Cox proportional-hazards models
Main finding
As reported in the abstract
Each group vs low gradual increaseAdjusted hazard ratio (95% CI)
Highest quartilebaseline TyG quartiles
1.28(1.19–1.39)
Medium stable
1.17(1.10–1.25)
High gradual increase
1.25(1.15–1.35)
- Patients with new CVD
- 11,099
- Trajectory patterns identified by Latent Class Trajectory Model (LCTM)
- 5
Observational data: associations, not effects.
Further findings
- Similar results between TyG trajectories and CVD subtypes
Original publication
Relationship between triglyceride-glucose index baselines and trajectories with incident cardiovascular diseases in the elderly population. Cardiovasc Diabetol. Published 3 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →