Lipids & metabolic liver disease
Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population
Authors' conclusion
Our study demonstrates a significant and independent association between the TyG index and both brachial and aortic diastolic BP in Chinese adults. Furthermore, the TyG index was found to be an independent predictor of hypertension.
Study context
- Population
- Chinese adults; Triglyceride-glucose (TyG) index = ln[fasting TG (mg/dL) × fasting glucose (mg/dL)/2]; central blood pressure (BP) by SphygmoCor
- Participants
- 715 adults
- Exposure
- TyG index tertiles
- Outcome
- Association of TyG index with brachial and aortic diastolic BP
Main finding
As reported in the abstract
Β (brachial diastolic BP)
2.66
P = 0.0084
Highest TyG tertile
Β (aortic diastolic BP)
3.96
P = 0.0001
Highest TyG tertile
- Brachial diastolic BP per TyG index, β
- 1.38 (P = 0.0310)
- Aortic diastolic BP per TyG index, β
- 2.38 (P = 0.0002)
Observational data: associations, not effects.
Further findings
| Outcome | Higher risk of hypertension | P value |
|---|---|---|
| Risk of hypertension | 95% | P = 0.0057 |
- Risk of hypertension — Higher risk of hypertension per one-unit increase in TyG index
- 46% (P = 0.0121)
Metabolic and cardiovascular parameters, prevalence of hypertension across TyG tertiles
- Significant differences among the groups
Original publication
Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population. Cardiovasc Diabetol. Published 3 January 2024. doi:10. 1186/ s12933-023-02068-z
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