Lipids & metabolic liver disease

Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population

Cardiovasc DiabetolPublished Cross-sectional study

Authors' conclusion

Our study demonstrates a significant and independent association between the TyG index and both brachial and aortic diastolic BP in Chinese adults. Furthermore, the TyG index was found to be an independent predictor of hypertension.

Study context

Population
Chinese adults; Triglyceride-glucose (TyG) index = ln[fasting TG (mg/dL) × fasting glucose (mg/dL)/2]; central blood pressure (BP) by SphygmoCor
Participants
715 adults
Exposure
TyG index tertiles
Outcome
Association of TyG index with brachial and aortic diastolic BP

Main finding

As reported in the abstract

Β (brachial diastolic BP)

2.66

P = 0.0084

Highest TyG tertile

Β (aortic diastolic BP)

3.96

P = 0.0001

Highest TyG tertile

Brachial diastolic BP per TyG index, β
1.38 (P = 0.0310)
Aortic diastolic BP per TyG index, β
2.38 (P = 0.0002)

Observational data: associations, not effects.

Further findings

OutcomeHigher risk of hypertensionP value
Risk of hypertension95%P = 0.0057
Risk of hypertension — Higher risk of hypertension per one-unit increase in TyG index
46% (P = 0.0121)

Metabolic and cardiovascular parameters, prevalence of hypertension across TyG tertiles

Significant differences among the groups

Original publication

Central and peripheral blood pressures in relation to the triglyceride-glucose index in a Chinese population. Cardiovasc Diabetol. Published 3 January 2024. doi:10.1186/s12933-023-02068-z

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