Lipids & metabolic liver disease
Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention
Authors' conclusion
The elevated TyG index is associated with an increased risk of cardiovascular events and predicts future MACEs in patients with CCS undergoing PCI independently of known cardiovascular risk factors, indicating that the TyG index may be a potential marker for risk stratification and prognosis in CCS patients undergoing PCI.
Study context
- Population
- Patients with chronic coronary syndrome undergoing percutaneous coronary intervention (PCI), China-Japan Friendship Hospital, 2019–2021
- Participants
- 1,353 patients
- Exposure
- Triglyceride-glucose (TyG) index tertiles
- Outcome
- MACE
- Follow-up
- 1-year follow-up
Methodological detailssingle-centre, Hospital Information System database
- Single-centre
- Hospital Information System database
Main finding
As reported in the abstract
1 year
Each group vs T1Fully adjusted HR (95% CI)P value
T2
1.343(1.054 ≈1.711)
T3
2.297(1.842 ≈2.864)
P < 0.001for trend- Highest TyG index: 59.5% increased risk of MACE
- adjusted HR 1.595 1.595 (95% CI 1.370 ≈1.855)
Observational data: associations, not effects.
Further findings
Predictive performance of TyG index for MACE
- AUC
- 0.810 (0.786, 0.834)
- χ2 likelihood ratio test
- χ2 = 7.474, P = 0.486
Dose-response (restricted cubic spline (RCS)) · 1 year
- TyG index nonlinearly associated with MACE risk
- P for nonlinear < 0.001
Subgroup analyses
- Results consistent with main analyses
Original publication
Prognostic value of triglyceride-glucose index in patients with chronic coronary syndrome undergoing percutaneous coronary intervention. Cardiovasc Diabetol. Published 28 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →