Relationship between stress hyperglycaemic ratio and incidence of in-hospital cardiac arrest in patients with acute coronary syndrome: a retrospective cohort study
Main finding · IHCA incidenceResult — go to the resultOdds ratio 2.1800 95% CI 1.2100–3.9300Authors' conclusion
In patients with ACS treated with PCI, the SHR was significantly associated with the incidence of IHCA. The SHR may be a useful predictor of the incidence of IHCA in patients with ACS. The addition of the SHR to the baseline risk model had an incremental effect on the predictive value of IHCA in patients with ACS treated with PCI.
Study context
- Population
- Patients with Acute Coronary Syndrome (ACS) who underwent Percutaneous Coronary Intervention (PCI) at the Affiliated Hospital of Zunyi Medical University
- Participants
- 1,939 patients
- Exposure
- Stress hyperglycaemic ratio (SHR) tertiles: T3 and T2 vs T1
- T1n = 646reference
- T2n = 646
- T3n = 647
- Outcome
- In-hospital cardiac arrest (IHCA) incidence
Methodological detailssingle-centre
- Single-centre
Main finding
IHCA incidence
Odds ratio
2.1800
95% CI 1.2100–3.9300
P = 0.0090
As reported in the abstract
- Overall in-hospital cardiac arrest (IHCA) incidence
- 4.1% (N = 80)
- SHR associated with IHCA, adjusted OR
- 2.6800 (95% CI 1.6200-4.4300; p<0.001)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| IHCA risk, DM subgroupT3vs T1Patients with DM | 2.4200 (1.0800–5.4300) | P = 0.0320 | |
| 0.20.5125Odds ratio (log scale) |
SHR and IHCA risk, STEMI subgroup
- Adjusted OR
- 3.0700 (95% CI 1.4100-6.6600; p = 0.0050)
SHR and IHCA risk, non-STEMI (NSTEMI) subgroup
- Adjusted OR
- 2.9900 (95% CI 1.1000-8.1100; p = 0.0310)
SHR and IHCA risk, diabetes mellitus (DM) subgroup
- Adjusted OR
- 2.5900 (95% CI 1.4200-4.7300; p = 0.0020)
SHR and IHCA risk, non-DM subgroup
- Adjusted OR
- 3.3000 (95% CI 1.2700-8.5800; p = 0.0140)
Dose-response (restriction cubic spline (RCS))
- Dose-response relationship; increased IHCA risk when SHR higher than
- 1.773
Adding SHR to baseline risk model
- NRI ([0.0058-0.1409], p = 0.0332)
- 0.0734
- IDI ([0.0063-0.0374], p = 0.0060)
- 0.0218
Original publication
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