Stress hyperglycemia ratio linked to worse prognosis in Cardiac Intensive Care Unit patients: A retrospective observational study
Authors' conclusion
SHR is a valuable indicator for predicting poor outcomes in CICU patients. Its utility spans potential risk stratification and offers insights for tailoring prognostic treatments to CICU patients.
Study context
- Population
- Patients in the cardiac ICU (Cardiac Intensive Care Unit (CICU)), Medical Information Mart for Intensive Care IV and Second Affiliated Hospital of Wenzhou Medical University1,133 MIMIC-IV + 412 Wenzhou
- Exposure
- Elevated vs lower stress hyperglycemia ratio
- Outcome
- Short-term mortality and MACE
- Follow-up
- 1-year follow-up
Methodological detailsInverse Probability of Treatment Weighting (IPTW), two cohorts (MIMIC-IV and Second Affiliated Hospital of Wenzhou Medical University)
- IPTW
- Two cohorts (MIMIC-IV and Second Affiliated Hospital of Wenzhou Medical University)
Main finding
As reported in the abstract
Short-term mortality and MACEs
SHREstimate (95% CI)
Short-term mortality and MACEs
adjusted HR 1.63(1.15–2.30)
Inverse probability of treatment weighting
HR (IPTW) 1.47(1.05–2.05)
Observational data: associations, not effects.
Further findings
90-day mortality and MACE by stress hyperglycemia ratio (SHR) and diabetes status
- Increased SHR without diabetes had the highest 90-day mortality and MACE
Predictive capability (C-statistic) of SHR added to foundational model
- C-statistic, outperforming other hyperglycemia metrics
- 0.821
Original publication
Stress hyperglycemia ratio linked to worse prognosis in Cardiac Intensive Care Unit patients: A retrospective observational study. Diabetes Res Clin Pract. Published 1 March 2024. doi:10.
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