Regional, age-specific and sex-specific trends in the prevalence of overweight or obesity in type 1 diabetes from 1980 to 2020: a meta-analysis of 78 observational studies with 650,265 participants
Authors' conclusion
The overweight or obesity prevalence has been increasing in T1D during 1980-2020, which may contribute to the increased risk of the diabetic complications, especially cardiovascular diseases. Weight management may be one of unmet clinical needs for future T1D management.
Study context
- Population
- People with T1D; observational studies reporting overweight or obesity prevalence, PubMed, Embase and Cochrane searched from inception to March 2024
- Participants
- 650,265 people78 studies
- Outcome
- Temporal trends in overweight or obesity prevalence in T1D
Methodological detailsrandom-effect model
- Random-effect model
Pooled result
As reported in the abstract
Obesity prevalence, adults with T1D · 1985-1990 to 2015-2020
- Obesity prevalence, adults, 1985-1990
- 3.3% (95%CI 2.1-5.0)
- Obesity prevalence, adults, 2015-2020
- 23.7% (95%CI 17.9-30.1)
- Overweight prevalence, adults, sustained upward trajectory, by 2015-2020
- 31.4% (95%CI 25.6-37.5)
- Obesity prevalence, children and adolescents, start of 1990-2010
- 6.3% (95%CI 3.8-9.8)
- Obesity prevalence, children and adolescents, end of 1990-2010
- 12.2% (95%CI 7.2-18.3)
- Obesity prevalence, children and adolescents, 2010-2020 (declined modestly)
- 9.3% (95%CI 6.7-12.4)
- Overweight prevalence, children and adolescents, maintained over two decades
- ≈20%
Further pooled results
Obesity prevalence by sex and continent
- Obesity prevalence increased in both sexes
- People living in North America might exhibit the highest obesity prevalence across continents
Original publication
Regional, age-specific and sex-specific trends in the prevalence of overweight or obesity in type 1 diabetes from 1980 to 2020: a meta-analysis of 78 observational studies with 650,265 participants. Diabetes Res Clin Pract. Published 14 September 2025. doi:10.
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