The association between glycaemic variability and sleep quality and quantity in adults with type 1 and type 2 diabetes: A systematic review
Authors' conclusion
A potential association between sleep quality and glycaemic variability exists. However, associations with other sleep metrics remain elusive, with no discernible association between sleep duration and glycaemic variability in type 1 diabetes. Despite advancements in continuous glucose monitoring and ambulatory sleep monitoring, standardised sleep assessment methodologies are lacking in real-world studies. Establishing standard protocols for sleep assessment and defining optimal sleep targets are crucial for meaningful comparisons between studies. Understanding the complex interplay between sleep and glycaemic variability holds promise in improving diabetes management and sleep health.
Study context
- Population
- Adults with T1D and T2D; Medline, EMBASE and Cochrane Library searched 2002–March 202327 studies (T1D = 22)
- Outcome
- Relationship between sleep outcomes and glycaemic variability
Methodological detailsqualitative analysis, Limitations: moderate to high risk of bias, confounders, methodological heterogeneity, limited T2D data
- Qualitative analysis
- Limitations: moderate to high risk of bias, confounders, methodological heterogeneity, limited T2D data
Pooled result
As reported in the abstract
Studies measuring sleep quality reporting a significant association with glycaemic variability in T1D and T2D
5 out 7; 71%
Further pooled results
HCL pump interventions
- Varying sleep outcomes with improved glycaemic variability
- n = 12 studies
Sleep interventions
- Consistently enhanced sleep but not glycaemic variability
- n = 3 studies
Original publication
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