Real-world study of the multimorbidity and health service utilisation among individuals with non-diabetic hyperglycemia and type 2 diabetes mellitus in North West London
Authors' conclusion
Both NDH and T2DM were associated with significant multimorbidity alongside primary and secondary care utilisation. Given the morbidity highlighted with NDH, we highlight the need for earlier detection of NDH, recognition of multimorbidity associated with both NDH and T2DM, as well as the need for the further implementation of interventions to prevent progression to T2DM/multimorbidity.
Study context
- Population
- Adults in North West London (Discover London Secure Data Environment (SDE) dataset), 1 January 2015–31 December 2020
- Participants
- 152,384 / 124,190 / 11,626
- Exposure
- Non-diabetic hyperglycemia (NDH) and T2D vs thyroid disease without NDH/T2D
- NDHn = 152,384
- T2DMn = 124,190
- Controln = 11,626reference
- Outcome
- Multimorbidity: three most common comorbidities
Methodological detailsreal-world, Discover London Secure Data Environment dataset
- Real-world
- Discover London Secure Data Environment dataset
Main finding
As reported in the abstract
Hypertension
| Outcome | NDH | T2DM | Control |
|---|---|---|---|
| Hypercholesterolemia | 37.5% | — not stated in the abstract | 24.4% |
| Obesity | 29.8% | 45.8% | — not stated in the abstract |
| Retinopathy | — not stated in the abstract | 68.7% | — not stated in the abstract |
| Depression | — not stated in the abstract | — not stated in the abstract | 30.8% |
— not stated in the abstract
- NDH or T2DM without at least one disease state of interest
- 13.1%
Observational data: associations, not effects.
Further findings
Primary care contacts per individual per year
| Outcome | NDH | T2DM | Control |
|---|---|---|---|
| Inpatient admissions | 282,371 events | 314,880 events | 27,881 events |
| Prescription of drugs used to treat T2D | 18.2% | 88.1% | — not stated in the abstract |
— not stated in the abstract
- Prescription of drugs used to treat T2D — Individuals with NDH developing T2D
- approximately one in five
Original publication
Real-world study of the multimorbidity and health service utilisation among individuals with non-diabetic hyperglycemia and type 2 diabetes mellitus in North West London. BMJ Open Diabetes Res Care. Published 8 August 2024. doi:10.
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