Evaluating the Effectiveness of the Reducing Weight With Intensive Dietary Support ( REWIND ) Programme on Type 2 Diabetes Remission
Authors' conclusion
Participation in REWIND was associated with modest improvements in weight, medication use and diabetes remission compared with usual care.
Study context
- Population
- People with T2D eligible for the REWIND programme, primary care, North West London
- Participants
- 1,051 vs 66,376
- Exposure
- REWIND programme vs no referral
- REWINDn = 1,051
- Controlsn = 66,376reference
- Outcome
- Weight, glucose-lowering medication prescribing, remission and glycaemic control
- Follow-up
- 12 months
Methodological detailsprimary care electronic health records, inverse probability weighting, average treatment effects on the treated
- Primary care electronic health records
- Inverse probability weighting
- Average treatment effects on the treated
Main finding
As reported in the abstract
Each group vs controlsWeight change, kg (95% CI)
REWIND
−2.1(−2.7 to −1.5)
- REWIND
- glucose-lowering medication prescribing −12.2% (95% CI −13.1 to −11.3)
- REWIND
- remission +4.2% (95% CI 3.9–4.5)
Observational data: associations, not effects.
Further findings
| Outcome | Increase in remission (CI) |
|---|---|
| Remission in programme completers · 12 monthsProgramme completers vs Controls | +8.1% (7.8%–8.5%) |
Remission by pathway · 12 months
- Total diet replacement pathway: increase in remission
- +6.9% [6.1-6.8]
- Low-carbohydrate pathway: increase in remission
- +2.9% [2.6-3.2]
Remission in programme completers · 12 months
- Programme completers had greater improvements across outcomes
Original publication
Evaluating the Effectiveness of the Reducing Weight With Intensive Dietary Support ( REWIND ) Programme on Type 2 Diabetes Remission. Diabetes Obes Metab. Published 23 September 2026. doi:10. 1111/ dom. 71364
Composed by AI from the published abstract and checked against it. How Briefs are made →