Type 2 & other diabetes

Evaluating the Effectiveness of the Reducing Weight With Intensive Dietary Support ( REWIND ) Programme on Type 2 Diabetes Remission

Diabetes Obes MetabPublished Observational pre-post quasi-experimental study

Authors' conclusion

Participation in REWIND was associated with modest improvements in weight, medication use and diabetes remission compared with usual care.

Study context

Population
People with T2D eligible for the REWIND programme, primary care, North West London
Participants
1,051 vs 66,376
Exposure
REWIND programme vs no referral
  • REWINDn = 1,051
  • Controlsn = 66,376reference
Outcome
Weight, glucose-lowering medication prescribing, remission and glycaemic control
Follow-up
12 months
Methodological detailsprimary care electronic health records, inverse probability weighting, average treatment effects on the treated
  • Primary care electronic health records
  • Inverse probability weighting
  • Average treatment effects on the treated

Main finding

As reported in the abstract

Each group vs controlsWeight change, kg (95% CI)
REWIND
−2.1(−2.7 to −1.5)
REWIND
glucose-lowering medication prescribing −12.2% (95% CI −13.1 to −11.3)
REWIND
remission +4.2% (95% CI 3.9–4.5)

Observational data: associations, not effects.

Further findings

OutcomeIncrease in remission (CI)
Remission in programme completers · 12 monthsProgramme completers vs Controls+8.1% (7.8%–8.5%)

Remission by pathway · 12 months

Total diet replacement pathway: increase in remission
+6.9% [6.1-6.8]
Low-carbohydrate pathway: increase in remission
+2.9% [2.6-3.2]

Remission in programme completers · 12 months

Programme completers had greater improvements across outcomes

Original publication

Evaluating the Effectiveness of the Reducing Weight With Intensive Dietary Support ( REWIND ) Programme on Type 2 Diabetes Remission. Diabetes Obes Metab. Published 23 September 2026. doi:10.1111/dom.71364

Composed by AI from the published abstract and checked against it. How Briefs are made →

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