Osteoporosis, bone & mineral

Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review

Osteoporos IntPublished Systematic review and meta-analysis of diagnostic accuracy studies

Authors' conclusion

Radiomorphometric indices of the mandible can be useful as a screening tool to identify patients with low BMD, but should not be used as a diagnostic method.

Study context

Population
Studies of mandibular radiomorphometric indices for diagnosis of osteopenia and osteoporosis; PubMed Central, Web of Science and Scopus, searched August 202364 articles
Comparison
Mandibular radiomorphometric indices vs DXA BMD measurement
Outcome
Sensitivity and specificity of the indices for reduced BMD vs DXA
Methodological detailsPRISMA, QUADAS-2 quality assessment, SROC curves
  • PRISMA
  • QUADAS-2 quality assessment
  • SROC curves

Pooled result

As reported in the abstract

Detection of reduced BMD (best index: MCW ≤ 3 mm)
GroupSensitivitySpecificity
MCW ≤ 3 mm0.712 (95% CI, 0.477-0.870)0.804 (95% CI, 0.589-0.921)

MCW ≤ 3 mm

Sensitivity0.712 (95% CI, 0.477-0.870)
Specificity0.804 (95% CI, 0.589-0.921)

Original publication

Radiomorphometric indices of the mandible as indicators of decreased bone mineral density and osteoporosis – meta-analysis and systematic review. Osteoporos Int. Published 23 October 2023. doi:10.1007/s00198-023-06949-7

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