Race- and Neighborhood-Related Disparities Spanning the COVID-19 Pandemic: Trajectories of Combined Glycemic Control and BMI in Youth With Diabetes
Authors' conclusion
Race and neighborhood deprivation were independently associated with distinct glycemic and BMIZ trajectory classes in youth with diabetes, highlighting persistent and widening disparities associated with the COVID-19 pandemic.
Study context
- Population
- Adolescents 10–19 years old with T1D and T2D with ≥1 visit at a large pediatric hospital prepandemic (January 2018–February 2020) and pandemic (April 2020–August 2021)1,322 T1D
- Exposure
- Race (Black vs White) and neighborhood deprivation (Area Deprivation Index (ADI) tertiles) as predictors of combined HbA1c and BMIZ trajectory class
- Outcome
- Latent classes of combined BMIZ and HbA1c trajectories spanning the COVID-19 pandemic; predictors of class membership
Methodological detailsgroup-based trajectory models, multinomial logistic regression
- Group-based trajectory models
- Multinomial logistic regression
Main finding
As reported in the abstract
RRR
3.0
95% CI 1.3–6.8
Black vs White · class with worsening glycemic control and concurrent BMIZ decrease at pandemic onset
RRR
3.0
95% CI 1.3–6.8
Black vs White · class with progressively worsening glycemic control and obesity
RRR
1.9
95% CI 1.2–2.9
ADI tertile 3 vs ADI tertile 1 · class with stable obesity and glycemic control
Observational data: associations, not effects.
Further findings
T2D: trajectory classes
- Distinct trajectories
- 3
- Trajectories with worsening glycemic control and concurrent BMIZ decline at pandemic onset
- 2
Original publication
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