Incidence of Diabetes in Children and Adolescents During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis
Pooled result · T1D incidence rateResult — go to the resultIncidence rate ratio 1.14 95% CI 1.08–1.21Authors' conclusion
This study found that incidence rates of type 1 diabetes and DKA at diabetes onset in children and adolescents were higher after the start of the COVID-19 pandemic than before the pandemic. Increased resources and support may be needed for the growing number of children and adolescents with diabetes. Future studies are needed to assess whether this trend persists and may help elucidate possible underlying mechanisms to explain temporal changes.
Study context
- Population
- Youths younger than 19 years; studies with ≥12 months observation during and before the pandemic, published in English; searched January 1, 2020, to March 28, 202342 studies, incident cases
- Participants
- 102,984 participants
- Comparison
- During vs before the COVID-19 pandemic
- Outcome
- Change in the incidence rate of pediatric diabetes during vs before the COVID-19 pandemic
Methodological detailscommon and random-effects analysis, MOOSE reporting guideline
- Common and random-effects analysis
- MOOSE reporting guideline
Pooled result
T1D incidence rate · first year of the pandemic
Incidence rate ratio
1.14
95% CI 1.08–1.21
During pandemicvs Prepandemic
IRR 1.14 (95% CI 1.08–1.21)
As reported in the abstract
Further pooled results
| Outcome | IRR (95% CI) | |
|---|---|---|
| Diabetes incidence · months 13 to 24 of the pandemic | 1.27 (1.18–1.37) | |
| DKA incidence at new-onset diabetes | 1.26 (1.17–1.36) | |
| 0.512Incidence rate ratio (log scale) |
- DKA incidence at new-onset diabetes: 15 studies (35.7%)
T2D incidence
- Studies reporting incident T2D cases in both periods; no incidence rates reported, not pooled
- 10 studies (23.8%)
Original publication
Incidence of Diabetes in Children and Adolescents During the COVID-19 Pandemic: A Systematic Review and Meta-Analysis. JAMA Netw Open. Published 1 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →