Prognostic significance of the stress hyperglycemia ratio in critically ill patients
An erratum to this article was published (Cardiovasc Diabetol, 6 Dec 2024 ↗)
Authors' conclusion
There was a U-shaped association between SHR and short- and long-term mortality in critical ill patients, and the inflection point of SHR for poor prognosis was identified at an SHR value of 0.96.
Study context
- Population
- Patients admitted to the intensive care unit (ICU)
- Participants
- 8,978 patients
- Exposure
- Stress hyperglycemia ratio (SHR) categories and SHR as a continuous variable vs mortality
- Outcome
- In-hospital and 1-year all-cause mortality
Methodological detailsSHR categorized into uniform groups; logistic or Cox regression; restricted cubic spline analysis
- SHR categorized into uniform groups; logistic or Cox regression; restricted cubic spline analysis
Main finding
As reported in the abstract
- In-hospital mortality
- 825 (9.2%)
- Died within 1-year follow-up
- 3,130 (34.9%)
- Adverse events minimized within SHR range
- 0.75-0.99
- In-hospital mortality per 0.25 increase in SHR, OR
- 1.34 (1.25-1.44) (95% CI)
- In-hospital mortality per 0.25 decrease in SHR within 0.75-0.99 range, OR
- 1.38 (1.10-1.75) (95% CI)
Observational data: associations, not effects.
Original publication
Prognostic significance of the stress hyperglycemia ratio in critically ill patients. Cardiovasc Diabetol. Published 13 October 2023. doi:10. 1186/ s12933-023-02005-0
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