Diabetes complications

Diagnostic accuracy of smartphone-based artificial intelligence systems for detecting diabetic retinopathy: A systematic review and meta-analysis

Diabetes Res Clin PractPublished Systematic review and meta-analysis of diagnostic test accuracy studies

Authors' conclusion

Smartphone-based AI algorithms show high diagnostic accuracy for detecting DR. However, more high-quality comparative studies are needed to evaluate the effectiveness in real-world clinical settings.

Study context

Population
Patients with diabetes screened for diabetic retinopathy (DR); MEDLINE, Embase, Scopus, CINAHL Plus and Cochrane searched from inception to December 2022
Participants
3,931 patients6 studies
Comparison
Smartphone-based artificial intelligence (AI) systems vs expert human grader for DR detection
Outcome
Pooled sensitivity and specificity for any DR (ADR) and referable DR (RDR), analysed separately
Methodological detailsrandom-effects model
  • Random-effects model

Pooled result

As reported in the abstract

Pooled diagnostic accuracy for ADR and RDR
GroupAny DR (ADR) sensitivityADR specificityReferable DR (RDR) sensitivityRDR specificity
Smartphone-based AI88 %91.5 %98.2 %81.2 %

Smartphone-based AI

Any DR (ADR) sensitivity88 %
ADR specificity91.5 %
Referable DR (RDR) sensitivity98.2 %
RDR specificity81.2 %

Further pooled results

The overall risk of bias across the studies was low

Original publication

Diagnostic accuracy of smartphone-based artificial intelligence systems for detecting diabetic retinopathy: A systematic review and meta-analysis. Diabetes Res Clin Pract. Published 5 October 2023. doi:10.1016/j.diabres.2023.110943

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