Prognostic impact of type 2 diabetes mellitus and coronary microvascular dysfunction in patients undergoing rotational atherectomy during PCI
An erratum to this article was published (Cardiovasc Diabetol, 15 Sep 2025 ↗)
Main finding · MACEResult — go to the resultHazard ratio 5.61 95% CI 2.606–12.083Authors' conclusion
This study reveals that both T2DM and CMD are associated with the risk of MACEs in RA patients during the PCI. Combing T2DM and CMD can further improve the accessibility to predict the risk of MACEs.
Study context
- Population
- Patients undergoing rotational atherectomy during PCI, 3 medical centers
- Participants
- 452 patients
- Exposure
- DM vs non-DM; Coronary microvascular dysfunction (CMD) vs no CMD; DM + CMD vs others
- Outcome
- MACE: cardiac death, MI, target vessel revascularization and readmission for unstable angina
- Follow-up
- 24 months
Methodological detailsmulticenter, observational
- Multicenter
- Observational
Main finding
MACE
Hazard ratio
5.61
95% CI 2.606–12.083
P < 0.001
By group
DM + CMD
HR 5.61 (95% CI 2.606–12.083); P < 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | non-DM | DM | P value |
|---|---|---|---|
| Post-PCI angio-IMRLower in non-DM | 17.40 (unspecified 13.86–21.34) | 18.53 (unspecified 14.63–23.01) | P = 0.037 |
Original publication
Prognostic impact of type 2 diabetes mellitus and coronary microvascular dysfunction in patients undergoing rotational atherectomy during PCI. Cardiovasc Diabetol. Published 24 July 2025. doi:10.
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