Prevalence and prognostic impact of stress-induced hyperglycemia in patients with acute type A aortic dissection
Authors' conclusion
Approximately 40% of the patients with ATAAD had SIH, and were more likely to present with high-risk clinical features and receive non-surgical treatment. Severe SIH could be used as an independent predictor of increased short-term and long-term mortality risk and reflect the disease severity of ATAAD.
Study context
- Population
- Patients with confirmed acute type A aortic dissection (ATAAD) without diabetesconsecutively enrolled
- Participants
- 1,098 patients
- Exposure
- Mild to moderate stress-induced hyperglycemia (SIH) and severe SIH vs normoglycemia
- Mild to moderate SIHn = 361
- Severe SIHn = 60
- Outcome
- Prevalence of SIH
- Follow-up
- Admission
Methodological detailsconsecutive enrolment, multivariate regression analysis
- Consecutive enrolment
- Multivariate regression analysis
Main finding
As reported in the abstract
- ATAAD patients with SIH
- 421 (38.3%)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| 30-day mortality · 30 daysSevere SIHvs NormoglycemiaMultivariate regression analysis | 3.773 (1.004–14.189) | P = 0.0494 | |
| 1-year mortalitySevere SIHvs NormoglycemiaMultivariate regression analysis | 3.522 (1.018–12.189) | P = 0.0469 | |
| 0.050.21520Odds ratio (log scale) |
High-risk clinical manifestations and conservative treatment
- Proportion of high-risk clinical manifestations and conservative treatment greater with SIH vs normoglycemia
Original publication
Prevalence and prognostic impact of stress-induced hyperglycemia in patients with acute type A aortic dissection. Diabetes Res Clin Pract. Published 5 July 2023. doi:10.
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