Prevalence and Predictors of Subclinical Cardiomyopathy in Patients With Type 2 Diabetes in a Health System
Authors' conclusion
In this single-center, EHR cohort, the prevalence of DbCM varies from 9% to 64%, with a higher prevalence with older age and Hispanic ethnicity.
Study context
- Population
- Adults with T2D free of cardiovascular disease (CVD) with available data on heart failure (HF) risk in a single-centre electronic health record (EHR)
- Participants
- 1,921 adults
- Outcome
- Prevalence of diabetic cardiomyopathy (DbCM): least restrictive ≥1, intermediate ≥2, most restrictive 3 echocardiographic abnormalities (left atrial enlargement, LV hypertrophy, diastolic dysfunction)
Methodological detailssingle-centre, EHR-based
- Single-centre
- EHR-based
Main finding
As reported in the abstract
DbCM prevalence, overall cohort
Prevalence, most restrictive definition
8.7%
Prevalence, least restrictive definition
64.4%
Observational data: associations, not effects.
Further findings
Diabetic cardiomyopathy (DbCM) prevalence by age, sex, race and ethnicity
- Across all definitions, older age and Hispanic ethnicity associated with a higher proportion of DbCM
- Females had a higher prevalence than males only in the most restrictive definition
- Chi-squared test
Predictors of DbCM (multivariable-adjusted logistic regression)
- Higher systolic blood pressure, higher creatinine and longer QRS duration associated with higher risk of DbCM across all definitions
Original publication
Prevalence and Predictors of Subclinical Cardiomyopathy in Patients With Type 2 Diabetes in a Health System. J Diabetes Sci Technol. Published 8 December 2023. doi:10.
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