Association of Continuous Glucose Monitoring Metrics with Incident Diabetic Retinopathy: A Real-World Long-Term Study
Authors' conclusion
these associations (except ARV) remained significant after landmark HbA1c adjustment and were stronger than for landmark HbA1c itself, suggesting that CGM metrics provide more informative risk stratification than HbA1c alone.
Study context
- Population
- Veterans with T1D (34%) or T2D (66%) who initiated Dexcom continuous glucose monitoring (CGM) between 2015 and 2022, with ≥10 days of data over a 6-month landmark period; CGM data merged with electronic health records (EHR)
- Participants
- 2,253 veterans
- Exposure
- CGM metrics and landmark HbA1c as predictors of incident diabetic retinopathy (DR)
- Outcome
- Incident DR, defined from EHR diagnoses
- Follow-up
- Up to 4 years from CGM initiation
Methodological detailsreal-world, 6-month landmark period, multivariable Cox models
- Real-world
- 6-month landmark period
- Multivariable Cox models
Main finding
As reported in the abstract
Incident DR · up to 4 years
Incident DR events
99
Observational data: associations, not effects.
Original publication
Association of Continuous Glucose Monitoring Metrics with Incident Diabetic Retinopathy: A Real-World Long-Term Study. Diabetes Technol Ther. Published 23 January 2026. doi:10. 1177/ 15209156261416922
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