Diabetes technology

Association of Continuous Glucose Monitoring Metrics with Incident Diabetic Retinopathy: A Real-World Long-Term Study

Diabetes Technol TherPublished Retrospective cohort study

Authors' conclusion

these associations (except ARV) remained significant after landmark HbA1c adjustment and were stronger than for landmark HbA1c itself, suggesting that CGM metrics provide more informative risk stratification than HbA1c alone.

Study context

Population
Veterans with T1D (34%) or T2D (66%) who initiated Dexcom continuous glucose monitoring (CGM) between 2015 and 2022, with ≥10 days of data over a 6-month landmark period; CGM data merged with electronic health records (EHR)
Participants
2,253 veterans
Exposure
CGM metrics and landmark HbA1c as predictors of incident diabetic retinopathy (DR)
Outcome
Incident DR, defined from EHR diagnoses
Follow-up
Up to 4 years from CGM initiation
Methodological detailsreal-world, 6-month landmark period, multivariable Cox models
  • Real-world
  • 6-month landmark period
  • Multivariable Cox models

Main finding

As reported in the abstract

Incident DR · up to 4 years

Incident DR events

99

Observational data: associations, not effects.

Original publication

Association of Continuous Glucose Monitoring Metrics with Incident Diabetic Retinopathy: A Real-World Long-Term Study. Diabetes Technol Ther. Published 23 January 2026. doi:10.1177/15209156261416922

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