Gestational diabetes & diabetes in pregnancy
Preterm Labor and Hypertensive Disorders in Adolescent Pregnancies With Diabetes Between 2006 and 2019
Authors' conclusion
Diabetes, which is increasing among adolescents, is a significant risk factor for preterm labor and hypertensive disorders. Though the absolute number of adolescent pregnancies is decreasing, rates of hypertensive disorders have increased. Appropriate interventions are needed to ensure healthy outcomes for adolescents who are pregnant.
Study context
- Population
- Adolescents (≤20 years old) with labor and delivery admissions in the national Kids' Inpatient Database, years 2006, 2009, 2012, 2016 and 2019
- Participants
- 1,843,139 adolescents
- Exposure
- Adolescent pregnancies with T1D, T2D or GDM vs without diabetes
- Outcome
- Hypertensive disorders and preterm labor
Methodological detailsnational database (Kids' Inpatient Database), weighted logistic regression
- National database (Kids' Inpatient Database)
- Weighted logistic regression
Main finding
As reported in the abstract
Hypertensive disorders
Each group vs noneAdjusted odds ratio (95% CI)P value
T1D
4.32(3.94–4.74)
P < 0:001T2D
4.18(3.79–4.61)
GDM
1.99(1.89–2.10)
Observational data: associations, not effects.
Further findings
| Outcome | T1D | T2D | GDM | None | aOR (95% CI) | P value | |
|---|---|---|---|---|---|---|---|
| Preterm laborT1Dvs None | 21.5% | 16.8% | 6.8% | 5.7% | 4.53 (4.09–5.02) | P < 0:001 | |
| Preterm laborT2Dvs None | 3.35 (2.96–3.78) | ||||||
| Preterm laborGDMvs None | 1.18 (1.08–1.28) | ||||||
| Hypertensive disorders by study year2019vs 2006 | 1.85 (1.77–1.94) | ||||||
| 0.20.5125Adjusted odds ratio (log scale) |
- Preterm labor: p <0:001 for prevalence across groups
Preterm labor
- Disparities by race/ethnicity, insurance and income
Overall prevalence among admissions
- T1D
- 0.2%
- T2D
- 0.2%
- GDM
- 0.7%
- Hypertensive disorders
- 10.1%
- Preterm labor
- 5.8%
Original publication
Preterm Labor and Hypertensive Disorders in Adolescent Pregnancies With Diabetes Between 2006 and 2019. Pediatr Diabetes. Published 18 October 2024. doi:10.
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