Gestational diabetes & diabetes in pregnancy

Gestational Diabetes Mellitus Is Associated With Adverse Outcomes in Singleton Pregnancies Conceived via Assisted Reproductive Technology: A Nationwide Inpatient Sample Analysis, 2008–2020

Endocr PractPublished Retrospective cohort study

Authors' conclusion

GDM was significantly associated with adverse maternal and fetal outcomes in singleton pregnancies conceived via ART.

Study context

Population
Singleton pregnancies conceived via assisted reproductive technology, U.S. Nationwide Inpatient Sample 2008–2020after matching
Participants
9,625 women
Exposure
Gestational diabetes mellitus (GDM) vs no GDM
  • GDMn = 1,925
  • Without GDMn = 7,700reference
Outcome
Adverse maternal and fetal outcomes
Methodological detailspropensity-score matched, nationwide database (U.S. Nationwide Inpatient Sample 2008–2020)
  • Propensity-score matched
  • Nationwide database (U.S. Nationwide Inpatient Sample 2008–2020)

Main finding

As reported in the abstract

GDM vs Without GDMOdds ratio (95% CI)
Preeclampsia
1.24(1.03–1.50)
Placenta previa
1.34(1.08–1.66)
Cesarean delivery
1.30(1.18–1.44)
Induction of labor
1.14(1.02–1.28)
Extended hospital stay
1.48(1.24–1.76)
Preterm birth
1.30(1.10–1.53)
Large for gestational age/fetal macrosomia
1.54(1.26–1.90)

Observational data: associations, not effects.

Further findings

Stratified and interaction analyses

Generally similar associations across subgroups; formal interaction analyses identified significant interactions for selected outcomes

Original publication

Gestational Diabetes Mellitus Is Associated With Adverse Outcomes in Singleton Pregnancies Conceived via Assisted Reproductive Technology: A Nationwide Inpatient Sample Analysis, 2008–2020. Endocr Pract. Published 6 September 2026. doi:10.1016/j.eprac.2026.08.023

Composed by AI from the published abstract and checked against it. How Briefs are made →

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