Gestational diabetes & diabetes in pregnancy
Prevalence of gestational diabetes mellitus risk factors in singleton pregnancies obtained by assisted reproductive technology: An observational, retrospective, real-world study from a pregnancy registry
Authors' conclusion
Prevalence of GDM traditional risk factors in singleton ART pregnancies complicated by GDM is considerable. Such pregnancies need appropriate clinical attention because of the risk of adverse outcomes.
Study context
- Population
- Women with singleton pregnancy obtained by Assisted Reproductive Technology (ART) and complicated by gestational diabetes mellitus (GDM), consecutively cared for at a specialized center for diabetes and pregnancy care; mean age 40.4 ± 4.7 years, mean pre-pregnancy BMI 26.3 ± 6.2 kg/m²
- Participants
- 50 women
- Outcome
- Prevalence of GDM risk factors
Methodological detailsobservational, real-world, pregnancy registry, single specialized center
- Observational
- Real-world
- Pregnancy registry
- Single specialized center
Main finding
As reported in the abstract
Prevalence of GDM traditional risk factors
- Age ≥ 35 years
- 94 %
- Family history of diabetes
- 44 %
- Overweight
- 29 %
- Obesity
- 19 %
- 1 risk factor
- 28 %
- 2 risk factors
- 46 %
- 3 risk factors
- 20 %
- 4 risk factors
- 4 %
- 5 risk factors
- 2 %
Observational data: associations, not effects.
Further findings
Pre-pregnancy weight and BMI across the 5 risk-factor groups
- Pre-pregnancy weight differed significantly among the 5 groups, increasing with higher numbers of risk factors
- P < 0.0001
- Pre-pregnancy BMI differed significantly among the 5 groups, increasing with higher numbers of risk factors
- P < 0.0001
Neonatal outcomes across the 5 risk-factor groups
- Only neonatal hypoglycemia differed significantly among the groups, higher with more combined risk factors
- P = 0.03
Original publication
Prevalence of gestational diabetes mellitus risk factors in singleton pregnancies obtained by assisted reproductive technology: An observational, retrospective, real-world study from a pregnancy registry. Diabetes Res Clin Pract. Published 2 April 2024. doi:10.
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