Gestational diabetes & diabetes in pregnancy
Regression From Early GDM to Normal Glucose Tolerance and Adverse Pregnancy Outcomes in the Treatment of Booking Gestational Diabetes Mellitus Study
Authors' conclusion
Women with early GDM but normal OGTT at 24-28 weeks' gestation had pregnancy outcomes that were similar to those of individuals without GDM. Identifying early GDM likely to regress would allow treatment to be avoided.
Study context
- Population
- Women at <20 weeks' gestation with GDM risk factors recruited for an RCT of early GDM treatment; treated early GDM and late GDM (WHO 2013 criteria) excluded
- Participants
- 2,218 / 121 / 254
- Comparison
- GDM-Regression vs No-GDM vs GDM-Maintained
- No-GDMn = 2,218reference
- GDM-Regressionn = 121
- GDM-Maintainedn = 254
- Primary endpoint
- Pregnancy outcomes
Primary result
As reported in the abstract
Pregnancy complications
- Adjusted incidences of pregnancy complications similar between GDM-Regression and No-GDM
- GDM-Regression risk factor profiles and oral glucose tolerance test (OGTT) results generally fell between No-GDM and GDM-Maintained
- Logistic regression
Original publication
Regression From Early GDM to Normal Glucose Tolerance and Adverse Pregnancy Outcomes in the Treatment of Booking Gestational Diabetes Mellitus Study. Diabetes Care. Published 29 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →