Gestational diabetes & diabetes in pregnancy
Maternal Glycemic Status and Longitudinal Fetal Body Composition and Organ Volumes Based on Three-Dimensional Ultrasonography
Authors' conclusion
Body composition differed in fetuses of GDM-complicated pregnancies, including larger arm and abdominal measures across the second and third trimesters. Patterns were similar in IGT-complicated pregnancies except that they occurred later in gestation and with larger magnitudes. Future research should explore how lifestyle and medication may alter fetal fat accumulation trajectories among hyperglycemic pregnancies.
Study context
- Population
- Diverse U.S. singleton pregnancy cohort (2015–2019); up to five 3D ultrasound scans
- Participants
- 2,427 participants
- Exposure
- Gestational diabetes mellitus (GDM) or impaired glucose tolerance (IGT) vs normal glucose tolerance (NGT)
- Outcome
- Longitudinal 3D fetal body composition and organ volume trajectories
Methodological detailslongitudinal, singleton pregnancy cohort, linear mixed models, adjusted for covariates
- Longitudinal
- Singleton pregnancy cohort
- Linear mixed models
- Adjusted for covariates
Main finding
As reported in the abstract
- GDM vs NGT: larger fractional arm and fractional fat arm volumes
- 26 to 35 weeks
- GDM vs NGT: smaller fractional lean arm volume
- 17 to 22 weeks
- GDM vs NGT: larger abdominal area
- 24 to 40 weeks
Observational data: associations, not effects.
Original publication
Maternal Glycemic Status and Longitudinal Fetal Body Composition and Organ Volumes Based on Three-Dimensional Ultrasonography. Diabetes Care. Published 16 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →