Gestational diabetes & diabetes in pregnancy
Preconception and pregnancy artificially sweetened beverage consumption and its association with adverse pregnancy outcomes: findings from the Australian longitudinal study on women’s health
Authors' conclusion
Frequent ASB consumption during pregnancy is associated with a higher risk of GDM, while its association with HDP and PTB remains inconclusive.
Study context
- Population
- Women from the Australian Longitudinal Study on Women's Health (ALSWH)
- Participants
- 3,653 women
- Exposure
- Frequent artificially sweetened beverage (ASB) consumption vs none, preconception and during pregnancy
- Outcome
- Adverse pregnancy outcomes: GDM, hypertensive disorder of pregnancy (HDP), preterm birth (PTB)
Methodological detailslongitudinal, generalized linear mixed model, augmented inverse probability weighting
- Longitudinal
- Generalized linear mixed model
- Augmented inverse probability weighting
Main finding
As reported in the abstract
during pregnancy
Each group vs noneEstimate (95 % CI)
Frequent ASB
aRR for GDM 1.88(1.12–3.14)
Frequent ASB
aRR for HDP 1.59(0.86–2.93)
Frequent ASB
aRR for PTB 1.22(0.36–3.99)
- Frequent ASB
- average treatment effect (ATE) 0.06 (95 % CI 0.01–0.11)
Observational data: associations, not effects.
Further findings
Incidence of gestational diabetes mellitus (GDM), hypertensive disorder of pregnancy (HDP) and preterm birth (PTB) by exposure window
- Preconception exposure group: GDM, HDP, PTB
- 9.1 %, 6.7 %, 4.3 %
- Pregnancy exposure group: GDM, HDP, PTB
- 8.6 %, 7.5 %, 4.0 %
Preconception ASB exposure and all outcomes
- Association remains uncertain
Original publication
Preconception and pregnancy artificially sweetened beverage consumption and its association with adverse pregnancy outcomes: findings from the Australian longitudinal study on women’s health. Diabetes Res Clin Pract. Published 21 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →