Gestational diabetes & diabetes in pregnancy

Continuous Glucose Monitoring and Maternal and Neonatal Morbidity in Pregnant People With Type 1 Diabetes

J Diabetes Sci TechnolPublished Retrospective cohort study

Authors' conclusion

CGM metrics in the late second to early third trimester, a period of peak insulin resistance, may help to distinguish risk of HDP and LGA in gravidas with T1DM.

Study context

Population
Singleton gestations with T1D using Dexcom G6 continuous glucose monitoring (CGM), academic medical center, 2018–2022; preconception median HbA1c 6.5% (IQR 6.0, 7.1), BMI 24.8 kg/m² (IQR 21.9, 27.1)
Participants
87 participants
Exposure
CGM metrics by presence vs absence of adverse pregnancy outcomes
Outcome
CGM metrics (TIR, TAR, TBR, mean glucose) by adverse pregnancy outcome
Follow-up
Weeks 240 to 376
Methodological detailssingle academic medical center
  • Single academic medical center

Main finding

As reported in the abstract

Hypertensive disorders of pregnancy (HDP): higher TAR and mean glucose and lower TIR, weeks 240 to 376
P < .05
TIR, TAR and mean glucose evolution differed by HDP status, greatest divergence at 280 to 296 weeks
P ≤ .001

Observational data: associations, not effects.

Further findings

Had at least one adverse pregnancy outcome
71%

Original publication

Continuous Glucose Monitoring and Maternal and Neonatal Morbidity in Pregnant People With Type 1 Diabetes. J Diabetes Sci Technol. Published 4 November 2025. doi:10.1177/19322968251388119

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