Gestational diabetes & diabetes in pregnancy

Maternal Glucose and Neonatal Hypoglycemia in Pregnancy with Type 1 Diabetes: A Continuous Glucose Monitoring Cohort

Diabetes Technol TherPublished Retrospective cohort study

Study context

Population
Women with T1D in pregnancy with CGM data, and their neonates with routine capillary blood glucose measurements
Participants
60 mothers
Exposure
Maternal CGM glycaemic metrics vs neonatal hypoglycemia (NH)
Outcome
Association between maternal glycaemia and NH (thresholds <2.2 mmol/L and <2.6 mmol/L)

Main finding

As reported in the abstract

Neonates with NH <2.6 mmol/L

25

41.7%

Neonates with NH <2.2 mmol/L

19

31.7%

% TAR associated with NH <2.2 mmol/L, OR

1.047 (1.007-1.087), P = 0.01 (95% CI)

% TIR associated with NH <2.2 mmol/L, OR

0.951 (0.914-0.989), P = 0.01 (95% CI)

Observational data: associations, not effects.

Further findings

Neonatal characteristics with NH <2.2 mmol/L

Lower gestational age with NH <2.2 mmol/L
P = 0.019
Higher proportion exposed to antenatal corticosteroids with NH <2.2 mmol/L
P = 0.014
Higher proportion requiring neonatal ICU admission with NH <2.2 mmol/L
P = 0.009

Neonatal characteristics with NH <2.6 mmol/L

Similar associations; neonatal ICU admission rates did not reach statistical significance

Original publication

Maternal Glucose and Neonatal Hypoglycemia in Pregnancy with Type 1 Diabetes: A Continuous Glucose Monitoring Cohort. Diabetes Technol Ther. Published 2 June 2025. doi:10.1089/dia.2024.0477

Composed by AI from the published abstract and checked against it. How Briefs are made →

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