Gestational diabetes & diabetes in pregnancy
Comparative effectiveness of different glycemic criteria for the diagnosis of gestational diabetes mellitus: a target trial emulation
Main finding · LGA infantsResult — go to the resultRelative risk 0.96 95 % CI 0.90–1.02Authors' conclusion
Lower glycemic criteria increased GDM diagnosis 2.53 - fold compared to higher criteria and 1.80 - fold relative to intermediate criteria, yet risks of LGA newborns and other issues remained unchanged.
Study context
- Population
- Singleton pregnant women who took a 75-g OGTT at 24–32 weeks of gestation
- Participants
- 38,995 women
- Comparison
- Lower vs intermediate vs higher glycemic criteria for gestational diabetes mellitus (GDM) diagnosis
- Outcome
- Adverse birth outcomes, including large-for-gestational-age (LGA) infants
Methodological detailscloning, censoring and inverse probability weighting, log-binomial regression
- Cloning, censoring and inverse probability weighting
- Log-binomial regression
Main finding
LGA infants
Relative risk
0.96
95 % CI 0.90–1.02
By group
Lower criteriavs Higher criteria
RR 0.96 (95 % CI 0.90–1.02)
As reported in the abstract
Further findings
Women diagnosed with GDM
All outcomes
- All outcomes showed statistical significance and agreement with targeted trials
Original publication
Comparative effectiveness of different glycemic criteria for the diagnosis of gestational diabetes mellitus: a target trial emulation. Diabetes Res Clin Pract. Published 26 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →