Gestational diabetes & diabetes in pregnancy
Simplified gestational diabetes screening with a triaging fasting plasma glucose reduces the burden of oral glucose tolerance tests during pregnancy – A large tertiary comparative cohort study
Authors' conclusion
The simplified GDM screening strategy for significantly reduced OGTTs by over 80% without impacting perinatal outcomes. It suggests that prospective studies are necessary to further evaluate this approach.
Study context
- Population
- Singleton births from 20 weeks' gestation; excluded: no diagnostic glucose results from 13 weeks' gestation or incomplete screeningof 15,138 pregnancies
- Participants
- 12,035 births
- Exposure
- Simplified GDM screening with triaging fasting plasma glucose (FPG) vs conventional screening
- Simplifiedn = 4,650
- Conventionaln = 7,385reference
- Outcome
- OGTT avoided
Methodological detailscomparative, tertiary centre
- Comparative
- Tertiary centre
Main finding
As reported in the abstract
Simplified
82.9 %
Observational data: associations, not effects.
Further findings
GDM prevalence · lower with Simplified
P < 0.001
Perinatal outcomes, incl. large-for-gestational-age infants
- Perinatal outcomes, including the rate of large-for-gestational-age infants, were similar between the groups
Original publication
Simplified gestational diabetes screening with a triaging fasting plasma glucose reduces the burden of oral glucose tolerance tests during pregnancy – A large tertiary comparative cohort study. Diabetes Res Clin Pract. Published 1 February 2024. doi:10. 1016/ j. diabres. 2024. 111120
Composed by AI from the published abstract and checked against it. How Briefs are made →