Gestational diabetes & diabetes in pregnancy
Gestational diabetes mellitus and risk of long-term all-cause and cardiac mortality: a prospective cohort study
Authors' conclusion
GDM alone was not associated with an increased risk of all-cause and cardiac mortality, while overt diabetes was significantly associated with both types of mortality.
Study context
- Population
- Women with a pregnancy history, National Health and Nutrition Examination Survey (2007 to 2018)weighted 132,332,187
- Participants
- 10,327 women
- Exposure
- Gestational diabetes mellitus (GDM) alone and overt diabetes vs no diabetes
- GDM alonen = 510
- Overt diabetesn = 1,862
- Outcome
- All-cause and cardiac mortality
- Follow-up
- Median 6.7 years
Methodological detailsNHANES 2007–2018, linked to National Death Index, multivariable Cox regression
- NHANES 2007–2018
- Linked to National Death Index
- Multivariable Cox regression
Main finding
As reported in the abstract
All-cause mortality
Each group vs no diabetesHazard ratio (95% CI)
GDM alone
0.67(0.25–1.84)
Overt diabetes
1.95(1.62–2.35)
- Deaths
- 758
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Cardiac mortality · median follow-up 6.7 yearsGDM alonevs No diabetes | HR 1.48 (95% CI 0.50–4.39) | |
| Cardiac mortality · median follow-up 6.7 yearsOvert diabetesvs No diabetes | HR 2.37 (95% CI 1.69–3.32) | |
| Sensitivity analysis, women aged ≥50: all-cause and cardiac mortalityGDM alonevs No diabetes | HR (all-cause mortality) 1.14 (95% CI 0.33–3.95) | |
| Sensitivity analysis, women aged ≥50: all-cause and cardiac mortalityGDM alonevs No diabetes | HR (cardiac mortality) 1.74 (95% CI 0.49–6.20) | |
| 0.10.31310Ratio (log scale) |
Original publication
Gestational diabetes mellitus and risk of long-term all-cause and cardiac mortality: a prospective cohort study. Cardiovasc Diabetol. Published 1 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →