Gestational diabetes & diabetes in pregnancy
Effect of vitamin D combined with probiotic-assisted insulin pump on glucose-lipid metabolism, intestinal flora and pregnancy outcome in gestational diabetes mellitus
Authors' conclusion
Compared with insulin pump plus vitamin D therapy, the addition of probiotics may improve blood glucose and lipid metabolism in GDM patients, maintain intestinal microbiota balance, and reduce the risk of adverse pregnancy outcomes.
Study context
- Population
- Gestational diabetes mellitus (GDM) patients admitted to hospital, all receiving diet, nutrition and exercise guidance
- Participants
- 150 patients
- Comparison
- Insulin aspart pump + vitamin D + Viable Bifidobacterium Tablets vs insulin aspart pump + vitamin D
- Studyn = 75
- Controln = 75reference
Primary result
As reported in the abstract
Glycemic and lipid metabolic indices and gut microbiota after treatment
- HDL-C, Bifidobacterium and Lactobacillus counts increased, and FINS, FPG, 2hPG, HbA1c, LDL-C, TC, TG, Coccidioides, Enterobacteriaceae and Saccharomycetes counts reduced in both groups (P < 0.05)
- Study vs Control: P < 0.05
Further findings
Standard-reaching rate of blood glucose
P < 0.05
Safety
Overall incidence of adverse pregnancy outcomes
P < 0.05
Original publication
Effect of vitamin D combined with probiotic-assisted insulin pump on glucose-lipid metabolism, intestinal flora and pregnancy outcome in gestational diabetes mellitus. Endocr Pract. Published 24 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →