Gestational diabetes & diabetes in pregnancy

Glucose Challenge Test Values Within the Normal Range and Long‐Term Risk of Type 2 Diabetes by Pre‐Pregnancy BMI : A Retrospective Cohort Study

Diabetes Obes MetabPublished Retrospective cohort study

Authors' conclusion

Pre-pregnancy BMI and GCT values within the normal range can be used for further type 2 diabetes risk stratification, ranging from minimal risk among women with a GCT < 90 mg/dL and normal weight to substantially increased risk among women with pre-pregnancy overweight or obesity.

Study context

Population
Pregnant women aged 20–50 with normal (< 140 mg/dL) glucose challenge test (GCT) results, 2004–2022; mean age 32.7 years1,354 developed T2D
Participants
249,190 women
Exposure
GCT values within the normal range, combined with pre-pregnancy BMI categories
Outcome
T2D
Follow-up
Median 7 years

Main finding

As reported in the abstract

Each group vs normal BMI, GCT 70-89 mg/dLAdjusted hazard ratio (95% CI)
Normal BMI, GCT 130-140 mg/dL
14.7(6.2–33.3)
Obesity, GCT 130-140 mg/dL
145(67.7–309)

Observational data: associations, not effects.

Original publication

Glucose Challenge Test Values Within the Normal Range and Long‐Term Risk of Type 2 Diabetes by Pre‐Pregnancy BMI : A Retrospective Cohort Study. Diabetes Obes Metab. Published 23 August 2026. doi:10.1111/dom.71259

Composed by AI from the published abstract and checked against it. How Briefs are made →

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